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SB269970 HCl
CAS No. 261901-57-9
SB269970 HCl( SB-269970A )
Catalog No. M17459 CAS No. 261901-57-9
SB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 45 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 113 | In Stock |
|
| 25MG | 243 | In Stock |
|
| 50MG | 426 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSB269970 HCl
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NoteResearch use only, not for human use.
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Brief DescriptionSB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
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DescriptionSB269970 HCl, a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
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In Vitro——
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In VivoSB269970 hydrochloride (SB-269970A) (3-30 mg/kg; i.p.; once) significantly blocks amphetamine and ketamine-induced hyperactivity. Animal Model:Male C57BL6/J miceDosage:3, 10, 30 mg/kg Administration:Intraperitoneal injection; onceResult:Significantly blocked amphetamine and ketamine-induced hyperactivity.
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SynonymsSB-269970A
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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Recptor5-HT7
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number261901-57-9
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Formula Weight388.95
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Molecular FormulaC18H28N2O3S·HCl
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 30 mg/mL; 77.13 mM
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SMILESCl.CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hagan JJ, et al. Br J Pharmacol, 2000, 130(3), 539-548.
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